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Protoilludene synthase

Webb4.2 Carbon-oxygen lyases. 4.2.3 Acting on phosphates. 4.2.3.135 DELTA6-protoilludene synthase. IUBMB Comments. Isolated from the fungus Armillaria gallica. Delta6 … Webb28 aug. 2024 · Sesquiterpenes are common small-molecule natural products with a wide range of promising applications and are biosynthesized by sesquiterpene synthase (STS). Basidiomycetes are valuable and important biological resources. To date, hundreds of related sesquiterpenoids have been discovered in basidiomycetes, and the biosynthetic …

WO2012016912A1 - Protoilludene synthase - Google Patents

WebbIntroduction. The mevalonate pathway (MP) also known as the isoprenoid pathway or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway is an anabolic pathway … Webb(A) Gene structure-phylogenetic tree of 15 characterized Δ 6 -protoilludene synthases (see the Supporting Information). (B) Homology model of Δ 6 -protoilludene synthases. poly vfocus2 manual https://search-first-group.com

Isolation of a gene cluster from Armillaria gallica for the ... - PubMed

WebbProtoilludene synthase . Jan 31, 2013 - Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. The present invention relates to an isolated, recombinant or synthetic polynucleotide encoding a polypeptide with protoilludene synthase activity and comprising a sequence selected from the group consisting of a) ... Webb16 nov. 2024 · Protoilludene-type aryl esters are synthesized by the esterification of protoilludanol alcohol and aromatic precursors derived from orsellinic acid, and this … WebbENZYME entry: EC. 4.2.3.135. (2E,6E)-farnesyl diphosphate <=> Delta (6)-protoilludene + diphosphate. Isolated from the fungus Armillaria gallica. Delta (6)-Protoilludene is the … shannon knight.com

Cloning and Characterization of an Armillaria gallica cDNA …

Category:CloningandCharacterizationofan Armillariagallica cDNA ...

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Protoilludene synthase

GC-MS analysis of hydroxylated protoilludenes produced by …

Webbfor protoilludene production Liyang Yang 1†, Chonglong Wang 1†, Jia Zhou1,2 and Seon‑Won Kim1* Abstract Background: Protoilludene is a valuable sesquiterpene and serves as a precursor for several medicinal compounds and antimicrobial chemicals. It can be synthesized by heterologous expression of protoilludene synthase in Escheri- WebbThe present invention relates to an isolated polynucelotide encoding a polypeptide with protoilludene synthase activity and comprising a sequence selected from the group …

Protoilludene synthase

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Webb6-protoilludene Supplier Sponsors. Name: (4aS,7aS,7bR)-3,6,6,7b-tetramethyl-2,4,4a,5,7,7a-hexahydro-1H-cyclobuta[e]indene: CAS not found: NF0343: 3D/inchi: ... Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. Notes ... WebbProtoilludene synthase activity was determined using [1-3 H]-farnesyl diphosphate (PPP) (20 Ci/mmol) (Biotend) in assay buffer (50 mM MOPS, 20 mM MgCl 2, 5 mM 2 …

Webb28 juli 2011 · The present invention relates to an isolated polynucelotide encoding a polypeptide with protoilludene synthase activity and comprising a sequence selected from the group consisting of a) SEQ ID Nos. 1 or 14 of the attached sequence listing; b) a nucleic acid sequence complementary to SEQ ID Nos. 1 or 14; c) nucleic acid sequences which … Webb7 okt. 2024 · Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta 6-protoilludene (PubMed:24166732, PubMed:26239156). In presence of Ca 2+, a …

WebbOther name(s): 6-protoilludene synthase. Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, Δ 6-protoilludene-forming) Comments: Isolated from the … WebbEP2415865A1 EP11157878A EP11157878A EP2415865A1 EP 2415865 A1 EP2415865 A1 EP 2415865A1 EP 11157878 A EP11157878 A EP 11157878A EP 11157878 A …

WebbPurification, crystallization and preliminary X-ray diffraction analysis of Omp6, a protoilludene synthase from Omphalotus olearius M. B. Quin , G. Wawrzyn and C. …

WebbT1 - Purification, crystallization and preliminary X-ray diffraction analysis of Omp6, a protoilludene synthase from Omphalotus olearius. AU - Quin, Maureen B. AU - Wawrzyn, Grayson. AU - Schmidt-Dannert, Claudia. PY - 2013/5. Y1 - 2013/5. KW - Omphalotus olearius. KW - natural products. KW - protoilludene. KW - sesquiterpene synthases shannon knobelWebbInstead, mutagenesis informed by the three-dimensional structure for pentalenene synthase 92 and parallel studies with other terpene synthases lead to mutant enzymes that yielded significant levels of germacrene A (38), sometimes in combination with protoilludene (39), another possible premature termination product, with a direct and … polyvia formationWebbIn silico analyses identified a putative protoilludene synthesis gene, pie1, as being up-regulated in the mycorrhizal stage, in addition to the previously identified, co-regulated … shannon knollsWebb15 nov. 2024 · Lanosterol synthase (LS) is at the second branch point of the MVA synthesis pathway and is also a key enzyme. LS can catalyse the cyclization of 2,3-oxidized squalene to lanosterol. Additionally, in the liquid medium of G. lucidum , the … polyvia formation logoWebb27 mars 2015 · Cloning and Characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. J. Biol. Chem, 286 (2011), pp. 6871-6878. View PDF View article CrossRef View in Scopus Google Scholar. 37. polyvia formation rennesWebb1 maj 2013 · The successful identification and characterization of a 1,6- and a 1,10-cyclizing sesquiterpene synthase, as well as three 1,11-cyclizing Δ(6) -protoilludene … polyvia formation lyon siretWebb19 jan. 2016 · Protoilludene is a valuable sesquiterpene and serves as a precursor for several medicinal compounds and antimicrobial chemicals. It can be synthesized by … shannon knight realtor