WebSep 21, 2013 · Plasma holotranscobalamin (holoTC) transports active cobalamin. Decreased levels of holoTC have been considered to be the earliest marker of cobalamin … WebJan 1, 2007 · We examined the levels of holotranscobalamin in 32 subjects (n=32, f=18, m=14) with vitamin B 12 values within interval 154-300 pmol/L. These subjects were …
Vitamin-B12-Wert: Was bedeutet mein Wert? Fernarzt
WebThe ARCHITECT Active-B12 (Holotranscobalamin) assay is a chemiluminescent microparticle immunoassay (CMIA) for the quantitative determination of holotranscobalamin in human serum on the ARCHITECT i System. Active-B12 (Holotranscobalamin) is used as an aid in the diagnosis and treatment of vitamin B12 … WebThe value of HoloTC in subclinical B12 deficiency currently remains unclear because the diagnostic characteristics of HoloTC have not been independently evaluated with reference standard measurements that are better than MMA or red blood cell B12 [ 11, 13, 43 ]. color changing flowers experiment for kids
Holotranscobalamin and Total Transcobalamin in Human Plasma
WebMay 20, 2016 · The concentration of total vitamin B12 in serum is not a sufficiently sensitive or specific indicator for the reliable diagnosis of vitamin B12 deficiency. Victor Herbert proposed a model for the staged development of vitamin B12 deficiency, in which holotranscobalamin (HoloTC) is the first indicator of deficiency. Based on this model, a … WebDec 17, 2024 · Holo-Transcobalamin: Marker zur verbesserten Erkennung von Vitamin-B12-Mangelzuständen 17. Dezember 2024 von Dr. med. Kai-Jürgen Lüthgens Insbesondere bei älteren Patienten ist relativ häufig ein erniedrigter Vitamin-B12-Spiegel nachweisbar. Jüngeren Menschen haben etwa in 5 % einen Vitamin-B12-Mangel [1]. WebAug 2, 2024 · Definition. Holotranscobalamin, kurz Holo-TC, ist die metabolisch aktive Form von Vitamin B12 und ein Komplex, der aus Transcobalamin II (TC II) und Vitamin B12 besteht. Es wird als Frühmarker zur Diagnostik von Mangelzuständen an Vitamin B12 in … dr shamah office