Cytohesin-1
WebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and … WebFeb 23, 2024 · Initially, CYTH1 was identified in a protein-protein interaction screen and found to interact specifically with the cytoplasmic part of the integrin β2 chain of LFA-1 …
Cytohesin-1
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WebJun 6, 2000 · Cytohesin-1 comprises an N-terminal coiled-coil domain, which may aid in oligomerization, a central Sec7 domain and a C-terminal module including the pleckstrin homology (PH) domain and a polybasic region. Cytohesin-1 specifically binds to the intracellular domain of the β-2 integrin chain and has been implicated in the functional … WebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and coatamer assembly in the cell. Cytohesin-1 also has been reported to promote cellular adhesion via binding to the β2 integrin cytoplasmic domain.
WebFeb 23, 2024 · Abstract. Adhesion is a key component of hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow. Here, using an RNA interference screen, we identify cytohesin 1 (CYTH1) as a critical mediator of adhesive properties in primary human cord blood–derived hematopoietic stem and progenitor … WebNischarin is an intracellular tumor suppressor protein that interacts with the cytoplasmic domain of α5-integrin, discovered by us [ 49 ]. Overexpression of Nischarin blocks cell migration....
Web英文名称:Human Cytohesin Interacting Protein, CYTIP GENLISA™ ELISA . Krishgen: KBH2280: ... 中文名称:人类白细胞衍生趋化因子 1,LECT1 GENLISA™ ELISA试剂盒 . 英文名称:Human Leukocyte Cell Derived Chemotaxin 1, LECT1 GENLISA™ ELISA . Krishgen: KBH2292: WebAll lanes : Anti-Cytohesin 1 antibody [EPR10050] (ab154847) at 1/1000 dilution Lane 1 : Raji cell lysate Lane 2 : Jurkat cell lysate Lane 3 : HuT-78 cell lysate Lysates/proteins at 10 µg per lane. Predicted band size: 46 kDa.
WebThe presence of a Sec7 domain was noted by both groups, and cytohesin-1 GEP activity was soon reported. 23. The Sec7 domains of Gea2 24 and cytohesin-1 25 and −2 26 have the same overall conformation, with two domains of five α helices each, and amino acid sequences of all Sec7 domains have a high degree of identity. The active site is in ...
WebKeywords: systemic sclerosis; biomarker; calumenin; S100A6; cytohesin 2 1. Introduction Systemic sclerosis (Ssc) is a systemic autoimmune disease with incomplete known physiopathology. Its hallmark is represented by collagen deposition in various tissues that are accompanied by vascular injury [1]. As the clinical course of the disease can be ... bluetooth unlock allWebCytohesin-1 is required for Schwann cell migration and that phosphorylation of cytohesin-1 at the Tyr-382 position is important for migration. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. bluetooth unknown winows 10WebTDR Targets ID: 578688 Echinococcus granulosus, cytohesin 1 Source Database / ID: GeneDB pI: 8.4469 Length (AA): 449 MW (Da): 50086 Paralog Number: 0 bluetooth unknown artist toyotaWebCYTIP cytohesin 1 interacting protein [ (human)] Gene ID: 9595, updated on 29-Mar-2024 Summary The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. clem geo energy corpWebCytohesin proteins are ubiquitous and have been implicated in several functions including cell spreading and adhesion, chemotaxis, protein trafficking, and cytoskeletal … bluetooth unlockCytohesin-1 (CYTH1) is a member of the cytohesin family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of CYTHs with membranes. Memb… clem full formWebImmunoprecipitation with a cytohesin-1 polyclonal antibody and blotting with cytohesin-1 specific mAbs revealed that cytohesin-1 is highly expressed in neutrophils. By PCR analysis of a human x rodent hybrid panel, the B2-1 … bluetooth unkown devices