WebAcyclovir crystalluria is considered a rare adverse effect which is more commonly described if there is intravenous administration. However, it may also be associated with oral administration [9]. It is more common in immunosuppressed patients, probably due … WebAug 1, 2024 · Aciclovir [9- (2-hydroxyethoxymethyl)guanine] is an acyclic nucleoside in the class of nucleoside analogues. 112 It is a substrate and specific inhibitor of herpesvirus DNA polymerase, blocking DNA synthesis, and is effective against herpes simplex virus type 1 and 2 and varicella-zoster virus infections, as well as several other viruses.
Acute renal failure related to topical acyclovir - Clinical Advisor
WebFor decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir … WebJul 15, 2012 · Drug-induced nephrotoxicity appears to be attributed to renal tubular damage caused by acyclovir-induced crystalluria (Pathol Lab Med. 2002;126:753-754). Topical acyclovir is available by ... dr lothus
Crystalluria from Acyclovir Use NEJM
WebAcyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. It shows good in vitro activity against herpes simplex and varicella-zoster viruses. ... The most important adverse effect is crystalluria and elevated serum creatinine related to bolus intravenous administration. Other reported adverse effects ... WebMar 9, 2010 · Acyclovir is commonly used in transplant patients, herpes virus, and varicella zoster virus infections, and other patients who present with potential viral CNS infections; hence, clinicians must be familiar with … WebJul 8, 2009 · Acyclovir crystals in the urine of a 28-year-old woman are described. The patient received intravenous acyclovir for herpes encephalitis. The crystalluria was accompanied by impairment of the renal tubules as evidenced by increased urinary beta-2-microglobulin excretion. Consecutive series of 60 patients on oral acyclovir and 20 … cokodive army bomb discount code