WebFigure 1 IFN-γ and LPS cooperatively induce CCL2 in monocytic cells/macrophages. THP-1 monocytic cells, primary monocytes, and THP-1-derived macrophages were treated for 24h with IFN-γ (10 ng/mL) alone or in combination with LPS (10 ng/mL). Total RNA was extracted and Ccl2 mRNA expression was quantified by real-time RT-PCR. WebDOWNLOADS Most Popular Insights An evolving model The lessons of Ecosystem 1.0 Lesson 1: Go deep or go home Lesson 2: Move strategically, not conveniently Lesson 3: …
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WebCCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, … WebDec 23, 2024 · Abstract. Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the third leading cause of cancer death worldwide. Closely associated with liver inflammation and fibrosis, hepatocyte cell death is a common trigger for acute and chronic liver disease arising from different etiologies, including viral hepatitis, alcohol abuse, and … heba al-demerdash
Ecosystem 2.0: Climbing to the next level (2024)
WebMCP1 antibody LS-C139944 is an unconjugated mouse monoclonal antibody to human MCP1 (CCL2). Validated for Flow, Func, IF, IHC and WB. WebFeb 16, 2024 · In summary, CCL2 is an autophagy-related gene that plays a key role in regulating autophagy and apoptosis after SCI. Therefore, we further hypothesized that CCL2 inhibits autophagy after SCI through the PI3K/Akt signaling pathway, thereby increasing apoptosis. Materials and methods Bioinformatic analysis WebJun 17, 2024 · Methods: CCL2 and CCR2 expression were analyzed in human DLBCL cell lines and normal B lymphocytes by Western blot (WB) and qPCR. CCL2 and CCR2 genes were silenced by lentivirus infection. The proliferation, migration, apoptosis and signaling pathway were detected by CCK8, transwell, flow cytometry (FC) and WB, respectively. euphonia hifi köln